Kazuhide Inoue Selected Research

Purinergic P2 Receptors (ADP Receptor)

9/2022	The Role of ATP Receptors in Pain Signaling.
1/2019	Role of the P2X4 receptor in neuropathic pain.
11/2018	A state-of-the-art perspective on microgliopathic pain.
1/2017	Neuropharmacological Study of ATP Receptors, Especially in the Relationship between Glia and Pain.
1/2013	[Neuropharmacological study of ATP receptors and their role in neuropathic pain].
11/2012	[Role of the glia in neuropathic pain caused by peripheral nerve injury].
11/2010	Nerve injury-activated microglia engulf myelinated axons in a P2Y12 signaling-dependent manner in the dorsal horn.
1/2008	Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury.
11/2007	P2X receptors-mediated cytosolic phospholipase A2 activation in primary afferent sensory neurons contributes to neuropathic pain.
9/2007	[Neuropathic pain and ATP receptors in spinal microglia].

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Kazuhide Inoue Research Topics

Disease

56	Neuralgia (Stump Neuralgia) 01/2022 - 02/2004
54	Pain (Aches) 09/2022 - 02/2002
36	Hyperalgesia 01/2018 - 07/2003
22	Chronic Pain 09/2022 - 01/2004
22	Peripheral Nerve Injuries 01/2019 - 08/2003
21	Hypersensitivity (Allergy) 01/2021 - 07/2003
7	Inflammation (Inflammations) 01/2016 - 11/2007
3	Acute Pain 01/2016 - 08/2003
2	Fibrosis (Cirrhosis) 01/2017 - 12/2008
2	Hypertrophy 01/2016 - 12/2008
2	Neoplasms (Cancer) 08/2014 - 01/2003
2	Necrosis 03/2007 - 01/2006
2	Hyperthyroidism 04/2006 - 09/2005
1	Contact Dermatitis (Eczema, Contact) 01/2021
1	Astrocytoma (Pilocytic Astrocytoma) 01/2019
1	Fibromyalgia (Fibrositis) 01/2017
1	Chronic Renal Insufficiency 11/2016
1	Hypertension (High Blood Pressure) 01/2016
1	Nociceptive Pain 01/2016

Drug/Important Bio-Agent (IBA)

24	Adenosine Triphosphate (ATP)IBA 09/2022 - 05/2002
23	Purinergic P2 Receptors (ADP Receptor)IBA 09/2022 - 08/2003
15	Purinergic Receptors (Receptors, Purine)IBA 03/2022 - 02/2005
15	Purinergic P2X4 ReceptorsIBA 01/2022 - 01/2006
9	NucleotidesIBA 09/2022 - 06/2005
8	Analgesics (Analgesic Drugs)IBA 11/2020 - 04/2009
7	CytokinesIBA 01/2013 - 01/2006
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 01/2006
6	p38 Mitogen-Activated Protein KinasesIBA 03/2007 - 01/2004
5	Capsaicin (Zostrix)FDA Link 11/2020 - 02/2002
5	Morphine (MS Contin)FDA LinkGeneric 01/2018 - 11/2009
5	Opioid Analgesics (Opioids)IBA 01/2017 - 04/2009
5	Brain-Derived Neurotrophic Factor (BDNF)IBA 11/2011 - 12/2005
4	Pharmaceutical PreparationsIBA 09/2022 - 11/2010
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 05/2014
4	CationsIBA 01/2018 - 05/2006
4	Proteins (Proteins, Gene)FDA Link 01/2017 - 07/2006
4	Messenger RNA (mRNA)IBA 01/2017 - 09/2005
4	SB 203580IBA 03/2007 - 01/2004
3	Neurotransmitter Agents (Neurotransmitter)IBA 09/2022 - 01/2021
3	Monoclonal AntibodiesIBA 01/2022 - 03/2013
3	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021 - 08/2015
3	Duloxetine Hydrochloride (Cymbalta)FDA Link 11/2020 - 01/2016
3	ChemokinesIBA 08/2014 - 09/2011
3	gamma-Aminobutyric Acid (GABA)IBA 12/2012 - 12/2005
3	Freund's AdjuvantIBA 08/2012 - 11/2007
3	Adenosine (Adenocard)FDA LinkGeneric 09/2011 - 02/2004
3	Formaldehyde (Formol)FDA Link 07/2011 - 05/2002
3	Fibronectins (Fibronectin)IBA 04/2008 - 05/2006
3	Ion Channels (Ion Channel)IBA 04/2008 - 02/2002
3	Interleukin-6 (Interleukin 6)IBA 03/2007 - 01/2006
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2020 - 01/2016
2	AntibodiesIBA 01/2019 - 03/2007
2	Extracellular Matrix ProteinsIBA 01/2017 - 12/2008
2	Angiotensin IIIBA 01/2016 - 12/2008
2	GTP-Binding Proteins (G-Protein)IBA 01/2016 - 12/2008
2	purinoceptor P2Y6IBA 01/2016 - 12/2008
2	Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)IBA 01/2016 - 11/2011
2	Minocycline (Cyclops)FDA LinkGeneric 09/2014 - 05/2009
2	Chemokine CCL3IBA 08/2014 - 06/2014
2	CC ChemokinesIBA 08/2014 - 06/2014
2	LigandsIBA 08/2014 - 06/2009
2	Cell Surface ReceptorsIBA 01/2013 - 11/2009
2	Gabapentin (Neurontin)FDA LinkGeneric 12/2012 - 11/2010
2	InterleukinsIBA 08/2012 - 03/2007
2	EnzymesIBA 08/2012 - 01/2006
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 11/2011 - 01/2007
2	src-Family KinasesIBA 07/2011 - 01/2008
2	Platelet Activating FactorIBA 01/2011 - 09/2007
2	cangrelorIBA 11/2010 - 05/2008
2	Phospholipases (Phospholipase)IBA 05/2010 - 11/2007
2	platelet activating factor receptorIBA 05/2010 - 09/2007
2	Interleukin-1beta (Interleukin 1 beta)IBA 05/2010 - 01/2006
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 05/2009 - 01/2008
2	Phospholipases A2 (Phospholipase A2)IBA 05/2009 - 11/2007
2	Protein Kinases (Protein Kinase)IBA 03/2008 - 09/2007
2	U 0126 (UO 126)IBA 03/2008 - 09/2007
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 07/2006 - 01/2003
2	OligodeoxyribonucleotidesIBA 01/2004 - 08/2003
2	Protons (Proton)IBA 07/2003 - 02/2002
1	Insulin (Novolin)FDA Link 01/2022
1	cilnidipineIBA 01/2021
1	MafB Transcription FactorIBA 01/2019
1	Small Interfering RNA (siRNA)IBA 01/2019
1	MicroRNAs (MicroRNA)IBA 01/2019
1	GlucocorticoidsIBA 10/2016
1	Heterotrimeric GTP-Binding Proteins (Heterotrimeric G-Proteins)IBA 01/2016
1	AngiotensinsIBA 01/2016
1	ArrestinIBA 01/2016
1	Guanine NucleotidesIBA 01/2016
1	N,N''- 1,4- butanediylbis(N'- (3- isothiocyanatophenyl))thioureaIBA 01/2016
1	Carrier Proteins (Binding Protein)IBA 01/2016
1	NP-1815-PXIBA 01/2016
1	Serotonin (5 Hydroxytryptamine)IBA 01/2016
1	Gastrin-Releasing PeptideIBA 08/2015

Therapy/Procedure

5	Therapeutics 11/2016 - 08/2003
3	Oral Administration 01/2016 - 05/2008
3	Spinal Injections 06/2014 - 05/2006
3	Ligation 11/2010 - 01/2006
2	Drug Therapy (Chemotherapy) 08/2014 - 11/2010
1	Laminectomy 09/2015